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Asynchronous transcriptional silencing of individual retroviral genomes in embryonic cells

BACKGROUND: Retroviral DNAs are profoundly silenced at the transcriptional level in embryonic cell types. The transcriptional profile of pluripotent stem cells has been demonstrated to be extremely heterogeneous from cell to cell, and how the silencing of retroviral DNAs is achieved is not yet well...

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Hlavní autoři: Schlesinger, Sharon, Meshorer, Eran, Goff, Stephen P
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021621/
https://ncbi.nlm.nih.gov/pubmed/24742368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-11-31
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