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Asynchronous transcriptional silencing of individual retroviral genomes in embryonic cells

BACKGROUND: Retroviral DNAs are profoundly silenced at the transcriptional level in embryonic cell types. The transcriptional profile of pluripotent stem cells has been demonstrated to be extremely heterogeneous from cell to cell, and how the silencing of retroviral DNAs is achieved is not yet well...

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Detalhes bibliográficos
Main Authors: Schlesinger, Sharon, Meshorer, Eran, Goff, Stephen P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021621/
https://ncbi.nlm.nih.gov/pubmed/24742368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-11-31
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