Systematic Identification of Factors for Provirus Silencing in Embryonic Stem Cells

Embryonic stem cells (ESCs) repress the expression of exogenous proviruses and endogenous retroviruses (ERVs). Here, we systematically dissected the cellular factors involved in provirus repression in embryonic carcinomas (ECs) and ESCs by a genome-wide siRNA screen. Histone chaperones (Chaf1a/b), s...

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Publicado no:Cell
Main Authors: Yang, Bin Xia, EL Farran, Chadi A., Guo, Hong Chao, Yu, Tao, Fang, Hai Tong, Wang, Hao Fei, Schlesinger, Sharon, Seah, Yu Fen Samantha, Goh, Germaine Yen Lin, Neo, Suat Peng, Li, Yinghui, Lorincz, Matthew C., Tergaonkar, Vinay, Lim, Tit-Meng, Chen, Lingyi, Gunaratne, Jayantha, Collins, James J., Goff, Stephen P., Daley, George Q., Li, Hu, Bard, Frederic A., Loh, Yuin-Han
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686136/
https://ncbi.nlm.nih.gov/pubmed/26365490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.08.037
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