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Xist RNA Is Confined to the Nuclear Territory of the Silenced X Chromosome throughout the Cell Cycle

In mammalian female cells, one X chromosome is inactivated to prevent a dose difference in the expression of X-encoded proteins between males and females. Xist RNA, required for X chromosome inactivation, is transcribed from the future inactivated X chromosome (Xi), where it spreads in cis, to initi...

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Detalhes bibliográficos
Main Authors: Jonkers, Iris, Monkhorst, Kim, Rentmeester, Eveline, Grootegoed, J. Anton, Grosveld, Frank, Gribnau, Joost
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546918/
https://ncbi.nlm.nih.gov/pubmed/18625719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02269-07
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