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Precise BAC targeting of genetically polymorphic mouse ES cells
The use of bacterial artificial chromosomes (BACs) provides a consistent and high targeting efficiency of homologous recombination in embryonic stem (ES) cells, facilitated by long stretches of sequence homology. Here, we introduce a BAC targeting method which employs restriction fragment length pol...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3185440/ https://ncbi.nlm.nih.gov/pubmed/21737430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr550 |
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