Opiate Addiction Therapies and HIV-1 Tat: Interactive Effects on Glial [Ca(2+)]i, Oxyradical and Neuroinflammatory Chemokine Production and Correlative Neurotoxicity

Few preclinical studies have compared the relative therapeutic efficacy of medications used to treat opiate addiction in relation to neuroAIDS. Here we compare the ability of methadone and buprenorphine, and the prototypic opiate morphine, to potentiate the neurotoxic and proinflammatory ([Ca(2+)]i,...

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Publicado en:Curr HIV Res
Autores principales: Fitting, Sylvia, Zou, Shiping, El-Hage1, Nazira, Suzuki, Masami, Paris, Jason J., Schier, Christina J., Rodríguez, José W., Rodriguez, Myosotys, Knapp, Pamela E., Hauser, Kurt F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Bentham Science Publishers 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475822/
https://ncbi.nlm.nih.gov/pubmed/25760046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570162X1206150311161147
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