A central role for glial CCR5 in directing the neuropathological interactions of HIV-1 Tat and opiates

BACKGROUND: The collective cognitive and motor deficits known as HIV-associated neurocognitive disorders (HAND) remain high even among HIV+ individuals whose antiretroviral therapy is optimized. HAND is worsened in the context of opiate abuse. The mechanism of exacerbation remains unclear but likely...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Kim, Sarah, Hahn, Yun Kyung, Podhaizer, Elizabeth M, McLane, Virginia D, Zou, Shiping, Hauser, Kurt F, Knapp, Pamela E
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180355/
https://ncbi.nlm.nih.gov/pubmed/30305110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1320-4
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