CCR2 mediates increases in glial activation caused by exposure to HIV-1 Tat and opiates

To assess the role of CCL2/MCP-1 in opiate drug abuse and HIV-1 comorbidity, the effects of systemic morphine and intrastriatal HIV-1 Tat on macrophage/microglial and astroglial activation were assessed in wild type and CCR2 null mice. Tat and/or morphine additively increased the proportion of CCL2...

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Bibliografiset tiedot
Julkaisussa:J Neuroimmunol
Päätekijät: El-Hage, Nazira, Wu, Guanghan, Ambati, Jayakrishna, Bruce-Keller, Annadora J., Knapp, Pamela E., Hauser, Kurt F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2006
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310703/
https://ncbi.nlm.nih.gov/pubmed/16831471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2006.05.027
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