Opiate Addiction Therapies and HIV-1 Tat: Interactive Effects on Glial [Ca(2+)]i, Oxyradical and Neuroinflammatory Chemokine Production and Correlative Neurotoxicity

Few preclinical studies have compared the relative therapeutic efficacy of medications used to treat opiate addiction in relation to neuroAIDS. Here we compare the ability of methadone and buprenorphine, and the prototypic opiate morphine, to potentiate the neurotoxic and proinflammatory ([Ca(2+)]i,...

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Detalhes bibliográficos
Publicado no:Curr HIV Res
Main Authors: Fitting, Sylvia, Zou, Shiping, El-Hage1, Nazira, Suzuki, Masami, Paris, Jason J., Schier, Christina J., Rodríguez, José W., Rodriguez, Myosotys, Knapp, Pamela E., Hauser, Kurt F.
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475822/
https://ncbi.nlm.nih.gov/pubmed/25760046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570162X1206150311161147
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