Opiate Addiction Therapies and HIV-1 Tat: Interactive Effects on Glial [Ca(2+)]i, Oxyradical and Neuroinflammatory Chemokine Production and Correlative Neurotoxicity

Few preclinical studies have compared the relative therapeutic efficacy of medications used to treat opiate addiction in relation to neuroAIDS. Here we compare the ability of methadone and buprenorphine, and the prototypic opiate morphine, to potentiate the neurotoxic and proinflammatory ([Ca(2+)]i,...

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Bibliografiske detaljer
Udgivet i:Curr HIV Res
Main Authors: Fitting, Sylvia, Zou, Shiping, El-Hage1, Nazira, Suzuki, Masami, Paris, Jason J., Schier, Christina J., Rodríguez, José W., Rodriguez, Myosotys, Knapp, Pamela E., Hauser, Kurt F.
Format: Artigo
Sprog:Inglês
Udgivet: Bentham Science Publishers 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475822/
https://ncbi.nlm.nih.gov/pubmed/25760046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570162X1206150311161147
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