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Poly-microbial sepsis increases susceptibility to chronic viral infection and exacerbates CD8(+) T cell exhaustion
Patients who survive sepsis display suppressed immune functions, often manifested as an increased susceptibility to secondary infections. Recently, using a cecal-ligation and puncture (CLP) model of sepsis we showed that sepsis induces substantial and long-lasting changes in the available naive CD8(...
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| Gepubliceerd in: | J Immunol |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4475506/ https://ncbi.nlm.nih.gov/pubmed/25980007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402473 |
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