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Alterations in Ag-specific naïve CD4 T cell precursors after sepsis impairs their responsiveness to pathogen challenge()

Patients surviving the acute stages of sepsis develop compromised T cell immunity and increased susceptibility to infection. Little is known about the decreased CD4 T cell function after sepsis. We tracked the loss and recovery of endogenous Ag-specific CD4 T cell populations after cecal-ligation an...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Cabrera-Perez, Javier, Condotta, Stephanie A., James, Britnie R., Kashem, Sakeen W., Brincks, Erik L., Rai, Deepa, Kucaba, Tamara A., Badovinac, Vladimir P., Griffith, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412277/
https://ncbi.nlm.nih.gov/pubmed/25595784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401711
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