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Sustained and incomplete recovery of naïve CD8(+) T-cell precursors after sepsis contributes to impaired CD8(+) T-cell responses to infection
Patients who survive severe sepsis often display compromised immune function with impairment in innate and adaptive immune responses. These septic patients are highly susceptible to ‘secondary’ infections with intracellular pathogens that are usually controlled by CD8(+) T-cells. It is unknown when...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3578009/ https://ncbi.nlm.nih.gov/pubmed/23355736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202379 |
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