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Immune unresponsiveness to secondary heterologous bacterial infection after sepsis induction is TRAIL-dependent

Sepsis is the leading cause of death in most ICU’s, and patients who survive the hyper-inflammation that develops early during sepsis later display severely compromised immunity. Not only is there apoptosis of lymphoid and myeloid cells during sepsis that depletes these critical cellular components...

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Detalhes bibliográficos
Main Authors: Gurung, Prajwal, Rai, Deepa, Condotta, Stephanie A., Babcock, Jeffrey C., Badovinac, Vladimir P., Griffith, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159846/
https://ncbi.nlm.nih.gov/pubmed/21788440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101180
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