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Glucose uptake and Runx2 synergize to orchestrate osteoblast differentiation and bone formation
The synthesis of Type I collagen, the main component of the bone matrix, precedes the expression of Runx2, the earliest determinant of osteoblast differentiation. We hypothesized that the osteoblast's energetic needs might explain this apparent paradox. We show here that glucose, the main nutri...
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| Yayımlandı: | Cell |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4475280/ https://ncbi.nlm.nih.gov/pubmed/26091038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.05.029 |
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