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Osteoblastic γ-Aminobutyric Acid, Type B Receptors Negatively Regulate Osteoblastogenesis toward Disturbance of Osteoclastogenesis Mediated by Receptor Activator of Nuclear Factor κB Ligand in Mouse Bone

The prevailing view is that signaling machineries for the neurotransmitter GABA are also expressed by cells outside the CNS. In cultured murine calvarial osteoblasts, mRNA was constitutively expressed for both subunits 1 and 2 of metabotropic GABA(B) receptor (GABA(B)R), along with inhibition by the...

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Detalhes bibliográficos
Main Authors: Takahata, Yoshifumi, Takarada, Takeshi, Hinoi, Eiichi, Nakamura, Yukari, Fujita, Hiroyuki, Yoneda, Yukio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190880/
https://ncbi.nlm.nih.gov/pubmed/21828041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.253526
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