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HDAC4 integrates PTH and sympathetic signaling in osteoblasts

Parathyroid hormone (PTH) and the sympathetic tone promote Rankl expression in osteoblasts and osteoclast differentiation by enhancing cyclic adenosine monophosphate production through an unidentified transcription factor for PTH and through ATF4 for the sympathetic tone. How two extracellular cues...

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Bibliographic Details
Main Authors: Obri, Arnaud, Makinistoglu, Munevver Parla, Zhang, Hong, Karsenty, Gerard
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068141/
https://ncbi.nlm.nih.gov/pubmed/24934156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201403138
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