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Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism

The broad expression of the insulin receptor suggests that the spectrum of insulin function has not been fully described. A cell type expressing this receptor is the osteoblast, a bone-specific cell favoring glucose metabolism through a hormone, osteocalcin, that becomes active once uncarboxylated....

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Detalhes bibliográficos
Main Authors: Ferron, Mathieu, Wei, Jianwen, Yoshizawa, Tatsuya, Fattore, Andrea Del, DePinho, Ronald A., Teti, Anna, Ducy, Patricia, Karsenty, Gerard
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910411/
https://ncbi.nlm.nih.gov/pubmed/20655470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.06.003
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