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Osteocalcin differentially regulates β cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice

The osteoblast-specific secreted molecule osteocalcin behaves as a hormone regulating glucose metabolism and fat mass in two mutant mouse strains. Here, we ask two questions: is the action of osteocalcin on β cells and adipocytes elicited by the same concentrations of the molecule, and more importan...

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Detalhes bibliográficos
Main Authors: Ferron, Mathieu, Hinoi, Eiichi, Karsenty, Gerard, Ducy, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278202/
https://ncbi.nlm.nih.gov/pubmed/18362359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711119105
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