INTERMITTENT INJECTIONS OF OSTEOCALCIN IMPROVE GLUCOSE METABOLISM AND PREVENT TYPE 2 DIABETES IN MICE

The uncarboxylated form of the osteoblast-specific secreted molecule osteocalcin is a hormone favoring glucose handling and increasing energy expenditure. As a result, the absence of osteocalcin leads to glucose intolerance in mice, while genetically modified mice with an increase in uncarboxylated...

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Bibliographic Details
Main Authors: Ferron, Mathieu, McKee, Marc D., Levine, Robert L., Ducy, Patricia, Karsenty, Gérard
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181267/
https://ncbi.nlm.nih.gov/pubmed/21550430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2011.04.017
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