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Intermolecular carbene S–H insertion catalysed by engineered myoglobin-based catalysts

The first example of a biocatalytic strategy for the synthesis of thioethers via an intermolecular carbene S–H insertion reaction is reported. Engineered variants of sperm whale myoglobin were found to efficiently catalyze this C–S bond forming transformation across a diverse set of aryl and alkyl m...

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Bibliografiset tiedot
Julkaisussa:Chem Sci
Päätekijät: Tyagi, Vikas, Bonn, Rachel B., Fasan, Rudi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Royal Society of Chemistry 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474517/
https://ncbi.nlm.nih.gov/pubmed/26101581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc00080g
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