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Highly diastereo- and enantioselective olefin cyclopropanation via engineered myoglobin-based catalysts

Using rational design, an engineered myoglobin-based catalyst capable of catalyzing the cyclopropanation of aryl-substituted olefins with catalytic proficiency (up to 46,800 turnovers) and excellent diastereo- and enantioselectivity (98–99.9%) was developed. This transformation could be carried out...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Angew Chem Int Ed Engl
Prif Awduron: Bordeaux, Melanie, Tyagi, Vikas, Fasan, Rudi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470557/
https://ncbi.nlm.nih.gov/pubmed/25538035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201409928
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