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Structure–Activity Relationships of N(6)-Benzyladenosine-5′-uronamides as A(3)-Selective Adenosine Agonists()

Adenosine analogues modified at the 5′-position as uronamides and/or as N(6)-benzyl derivatives were synthesized. These derivatives were examined for affinity in radioligand binding assays at the newly discovered rat brain A(3) adenosine receptor and at rat brain A(1) and A(2a) receptors. 5′-Uronami...

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Bibliographic Details
Published in:J Med Chem
Main Authors: Gallo-Rodriguez, Carola, Ji, Xiao-duo, Melman, Neli, Siegman, Barry D., Sanders, Lawrence H., Orlina, Jeraldine, Fischer, Bilha, Pu, Quanlong, Olah, Mark E., van Galen, Philip J. M., Stiles, Gary L., Jacobson, Kenneth A.
Format: Artigo
Language:Inglês
Published: 1994
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474279/
https://ncbi.nlm.nih.gov/pubmed/8126704
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