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Structure–Activity Relationships of 8-Styrylxanthines as A(2)-Selective Adenosine Antagonists(,)
A series of substituted 8-styryl derivatives of 1,3,7-alkylxanthines was synthesized as potential A(2)-selective adenosine receptor antagonists, and the potency at rat brain A(1)- and A(2)-receptors was studied in radioligand binding experiments. At the xanthine 7-position, only small hydrophobic su...
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| Foilsithe in: | J Med Chem |
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| Main Authors: | , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
1993
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5975975/ https://ncbi.nlm.nih.gov/pubmed/8496902 |
| Clibeanna: |
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