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8-(3-Chlorostyryl)caffeine (CSC) is a selective A(2)-adenosine antagonist in vitro and in vivo

An adenosine antagonist, 8-(3-chlorostyryl)caffeine (CSC), was shown previously to be 520-fold selective for A(2a)-adenosine receptors in radioligand binding assays in the rat brain. In reversing agonist effects on adenylate cyclase, CSC was 22-fold selective for A(2d) receptors in rat pheochromocy-...

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Bibliografiske detaljer
Main Authors: Jacobson, Kenneth A., Nikodijević, Olga, Padgett, William L., Gallo-Rodriguez, Carola, Maillard, Michel, Daly, John W.
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468328/
https://ncbi.nlm.nih.gov/pubmed/8495727
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