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Quantification of the In Vivo Potency of the Adenosine A(2) Receptor Antagonist 8-(3-Chlorostyryl)Caffeine

The purpose of the present study was to quantify the in vivo potency of the selective adenosine A(2a) antagonist CSC [8-(3-chlorostyryl)caffeine]. Four groups of conscious, normotensive rats received a continuous i.v. infusion of 0, 6, 12 and 24 μg/min/kg of CSC. During a steady-state infusion of CS...

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Publicado en:J Pharmacol Exp Ther
Autores principales: MATHÔT, RON A. A., GUBBENS-STIBBE, JOSY M., SOUDIJN, WILLEM, JACOBSON, KENNETH A., IJZERMAN, ADRIAAN P., DANHOF, MEINDERT
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473028/
https://ncbi.nlm.nih.gov/pubmed/7562557
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