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2-Substitution of N(6)-Benzyladenosine-5′-uronamides Enhances Selectivity for A(3) Adenosine Receptors
Adenosine derivatives bearing an N(6)-(3-iodobenzyl) group, reported to enhance the affinity of adenosine-5′-uronamide analogues as agonists at A(3) adenosine receptors (J. Med. Chem. 1994, 37, 636–646), were synthesized starting from methyl β-d-ribofuranoside in 10 steps. Binding affinities at A(1)...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3468333/ https://ncbi.nlm.nih.gov/pubmed/7932588 |
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