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2-Substitution of N(6)-Benzyladenosine-5′-uronamides Enhances Selectivity for A(3) Adenosine Receptors

Adenosine derivatives bearing an N(6)-(3-iodobenzyl) group, reported to enhance the affinity of adenosine-5′-uronamide analogues as agonists at A(3) adenosine receptors (J. Med. Chem. 1994, 37, 636–646), were synthesized starting from methyl β-d-ribofuranoside in 10 steps. Binding affinities at A(1)...

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Sonraí Bibleagrafaíochta
Main Authors: Kim, Hea O., Ji, Xiao-duo, Siddiqi, Suhaib M., Olah, Mark E., Stiles, Gary L., Jacobson, Kenneth A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1994
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468333/
https://ncbi.nlm.nih.gov/pubmed/7932588
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