SAMHD1 Limits HIV-1 Antigen Presentation by Monocyte-Derived Dendritic Cells

Monocyte-derived dendritic cells (MDDC) stimulate CD8(+) cytotoxic T lymphocytes (CTL) by presenting endogenous and exogenous viral peptides via major histocompatibility complex class I (MHC-I) molecules. MDDC are poorly susceptible to HIV-1, in part due to the presence of SAMHD1, a cellular enzyme...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Ayinde, Diana, Bruel, Timothée, Cardinaud, Sylvain, Porrot, Françoise, Prado, Julia G., Moris, Arnaud, Schwartz, Olivier
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2015
Aiheet:
Cellular Response to Infection
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473575/
https://ncbi.nlm.nih.gov/pubmed/25926647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00069-15
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