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SAMHD1 Restricts Herpes Simplex Virus 1 in Macrophages by Limiting DNA Replication

Macrophages play important roles in host immune defense against virus infection. During infection by herpes simplex virus 1 (HSV-1), macrophages acquire enhanced antiviral potential. Restriction of HSV-1 replication and progeny production is important to prevent viral spread, but the cellular mechan...

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Main Authors: Kim, Eui Tae, White, Tommy E., Brandariz-Núñez, Alberto, Diaz-Griffero, Felipe, Weitzman, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838123/
https://ncbi.nlm.nih.gov/pubmed/24067963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02291-13
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