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Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1

The human SAMHD1 protein is a novel retroviral restriction factor expressed in myeloid cells. Previous work has correlated the deoxynucleotide triphosphohydrolase activity of SAMHD1 with its ability to block HIV-1 and SIV(mac) infection. SAMHD1 is comprised of the sterile alpha motif (SAM) and histi...

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Detaylı Bibliyografya
Asıl Yazarlar: White, Tommy E., Brandariz-Nuñez, Alberto, Valle-Casuso, Jose Carlos, Amie, Sarah, Nguyen, Laura, Kim, Baek, Brojatsch, Jurgen, Diaz-Griffero, Felipe
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767443/
https://ncbi.nlm.nih.gov/pubmed/23158101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.10.029
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