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Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1
The human SAMHD1 protein is a novel retroviral restriction factor expressed in myeloid cells. Previous work has correlated the deoxynucleotide triphosphohydrolase activity of SAMHD1 with its ability to block HIV-1 and SIV(mac) infection. SAMHD1 is comprised of the sterile alpha motif (SAM) and histi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3767443/ https://ncbi.nlm.nih.gov/pubmed/23158101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.10.029 |
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