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Effects of human SAMHD1 Polymorphisms on HIV-1 Susceptibility
SAMHD1 is a human restriction factor that prevents efficient infection of macrophages, dendritic cells and resting CD4+ T cells by HIV-1. Here we explored the antiviral activity and biochemical properties of human SAMHD1 polymorphisms. Our studies focused on human SAMHD1 polymorphisms that were prev...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4101048/ https://ncbi.nlm.nih.gov/pubmed/25010268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.04.023 |
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