Identification of Cellular Proteins Interacting with the Retroviral Restriction Factor SAMHD1

Human and mouse SAMHD1 proteins block human immunodeficiency virus type 1 (HIV-1) infection in noncycling human monocytic cells by reducing the intracellular deoxynucleoside triphosphate (dNTP) concentrations. Phosphorylation of human SAMHD1 at threonine 592 (T592) by cyclin-dependent kinase 1 (CDK1...

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Hlavní autoři: St. Gelais, Corine, de Silva, Suresh, Hach, Jocelyn C., White, Tommy E., Diaz-Griffero, Felipe, Yount, Jacob S., Wu, Li
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019113/
https://ncbi.nlm.nih.gov/pubmed/24623419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00155-14
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