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Identification of Cellular Proteins Interacting with the Retroviral Restriction Factor SAMHD1
Human and mouse SAMHD1 proteins block human immunodeficiency virus type 1 (HIV-1) infection in noncycling human monocytic cells by reducing the intracellular deoxynucleoside triphosphate (dNTP) concentrations. Phosphorylation of human SAMHD1 at threonine 592 (T592) by cyclin-dependent kinase 1 (CDK1...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4019113/ https://ncbi.nlm.nih.gov/pubmed/24623419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00155-14 |
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