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SAMHD1 Limits HIV-1 Antigen Presentation by Monocyte-Derived Dendritic Cells
Monocyte-derived dendritic cells (MDDC) stimulate CD8(+) cytotoxic T lymphocytes (CTL) by presenting endogenous and exogenous viral peptides via major histocompatibility complex class I (MHC-I) molecules. MDDC are poorly susceptible to HIV-1, in part due to the presence of SAMHD1, a cellular enzyme...
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| 出版年: | J Virol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4473575/ https://ncbi.nlm.nih.gov/pubmed/25926647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00069-15 |
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