HIV-2 infects resting CD4+ T cells but not monocyte-derived dendritic cells

BACKGROUND: Human Immunodeficiency Virus-type 2 (HIV-2) encodes Vpx that degrades SAMHD1, a cellular restriction factor active in non-dividing cells. HIV-2 replicates in lymphocytes but the susceptibility of monocyte-derived dendritic cells (MDDCs) to in vitro infection remains partly characterized....

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Detalhes bibliográficos
Publicado no:Retrovirology
Main Authors: Chauveau, Lise, Puigdomenech, Isabel, Ayinde, Diana, Roesch, Ferdinand, Porrot, Françoise, Bruni, Daniela, Visseaux, Benoit, Descamps, Diane, Schwartz, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307230/
https://ncbi.nlm.nih.gov/pubmed/25582927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-014-0131-7
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