Genetic alterations of KDM4 subfamily and therapeutic effect of novel demethylase inhibitor in breast cancer

The histone lysine demethylase KDM4 subfamily, comprised of four members (A, B, C, and D), play critical roles in controlling transcription, chromatin architecture and cellular differentiation. We previously demonstrated that KDM4C is significantly amplified and overexpressed in aggressive basal-lik...

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Bibliografiske detaljer
Udgivet i:Am J Cancer Res
Main Authors: Ye, Qin, Holowatyj, Andreana, Wu, Jack, Liu, Hui, Zhang, Lihong, Suzuki, Takayoshi, Yang, Zeng-Quan
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2015
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473328/
https://ncbi.nlm.nih.gov/pubmed/26101715
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