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Genetic alterations of KDM4 subfamily and therapeutic effect of novel demethylase inhibitor in breast cancer
The histone lysine demethylase KDM4 subfamily, comprised of four members (A, B, C, and D), play critical roles in controlling transcription, chromatin architecture and cellular differentiation. We previously demonstrated that KDM4C is significantly amplified and overexpressed in aggressive basal-lik...
Uloženo v:
| Vydáno v: | Am J Cancer Res |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
e-Century Publishing Corporation
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4473328/ https://ncbi.nlm.nih.gov/pubmed/26101715 |
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