Genetic alterations of KDM4 subfamily and therapeutic effect of novel demethylase inhibitor in breast cancer

The histone lysine demethylase KDM4 subfamily, comprised of four members (A, B, C, and D), play critical roles in controlling transcription, chromatin architecture and cellular differentiation. We previously demonstrated that KDM4C is significantly amplified and overexpressed in aggressive basal-lik...

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Detaylı Bibliyografya
Yayımlandı:Am J Cancer Res
Asıl Yazarlar: Ye, Qin, Holowatyj, Andreana, Wu, Jack, Liu, Hui, Zhang, Lihong, Suzuki, Takayoshi, Yang, Zeng-Quan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: e-Century Publishing Corporation 2015
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473328/
https://ncbi.nlm.nih.gov/pubmed/26101715
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