Genetic alterations of KDM4 subfamily and therapeutic effect of novel demethylase inhibitor in breast cancer

The histone lysine demethylase KDM4 subfamily, comprised of four members (A, B, C, and D), play critical roles in controlling transcription, chromatin architecture and cellular differentiation. We previously demonstrated that KDM4C is significantly amplified and overexpressed in aggressive basal-lik...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Cancer Res
Prif Awduron: Ye, Qin, Holowatyj, Andreana, Wu, Jack, Liu, Hui, Zhang, Lihong, Suzuki, Takayoshi, Yang, Zeng-Quan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: e-Century Publishing Corporation 2015
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473328/
https://ncbi.nlm.nih.gov/pubmed/26101715
Tagiau: Ychwanegu Tag
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