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Genetic alterations of KDM4 subfamily and therapeutic effect of novel demethylase inhibitor in breast cancer

The histone lysine demethylase KDM4 subfamily, comprised of four members (A, B, C, and D), play critical roles in controlling transcription, chromatin architecture and cellular differentiation. We previously demonstrated that KDM4C is significantly amplified and overexpressed in aggressive basal-lik...

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書誌詳細
出版年:Am J Cancer Res
主要な著者: Ye, Qin, Holowatyj, Andreana, Wu, Jack, Liu, Hui, Zhang, Lihong, Suzuki, Takayoshi, Yang, Zeng-Quan
フォーマット: Artigo
言語:Inglês
出版事項: e-Century Publishing Corporation 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473328/
https://ncbi.nlm.nih.gov/pubmed/26101715
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