Uncoupling of Elastin Complex Receptor during In Vitro Aging Is Related to Modifications in Its Intrinsic Sialidase Activity and the Subsequent Lactosylceramide Production

Degradation of elastin leads to the production of elastin-derived peptides (EDP), which exhibit several biological effects, such as cell proliferation or protease secretion. Binding of EDP on the elastin receptor complex (ERC) triggers lactosylceramide (LacCer) production and ERK1/2 activation follo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Scandolera, Amandine, Rabenoelina, Fanja, Chaintreuil, Carine, Rusciani, Anthony, Maurice, Pascal, Blaise, Sébastien, Romier-Crouzet, Béatrice, El Btaouri, Hassan, Martiny, Laurent, Debelle, Laurent, Duca, Laurent
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473072/
https://ncbi.nlm.nih.gov/pubmed/26086247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129994
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge