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Uncoupling of Elastin Complex Receptor during In Vitro Aging Is Related to Modifications in Its Intrinsic Sialidase Activity and the Subsequent Lactosylceramide Production

Degradation of elastin leads to the production of elastin-derived peptides (EDP), which exhibit several biological effects, such as cell proliferation or protease secretion. Binding of EDP on the elastin receptor complex (ERC) triggers lactosylceramide (LacCer) production and ERK1/2 activation follo...

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التفاصيل البيبلوغرافية
الحاوية / القاعدة:	PLoS One
المؤلفون الرئيسيون:	Scandolera, Amandine, Rabenoelina, Fanja, Chaintreuil, Carine, Rusciani, Anthony, Maurice, Pascal, Blaise, Sébastien, Romier-Crouzet, Béatrice, El Btaouri, Hassan, Martiny, Laurent, Debelle, Laurent, Duca, Laurent
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Public Library of Science 2015
الموضوعات:	Research Article
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4473072/ https://ncbi.nlm.nih.gov/pubmed/26086247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129994
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Uncoupling of Elastin Complex Receptor during In Vitro Aging Is Related to Modifications in Its Intrinsic Sialidase Activity and the Subsequent Lactosylceramide Production

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