Uncoupling of Elastin Complex Receptor during In Vitro Aging Is Related to Modifications in Its Intrinsic Sialidase Activity and the Subsequent Lactosylceramide Production

Degradation of elastin leads to the production of elastin-derived peptides (EDP), which exhibit several biological effects, such as cell proliferation or protease secretion. Binding of EDP on the elastin receptor complex (ERC) triggers lactosylceramide (LacCer) production and ERK1/2 activation follo...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Scandolera, Amandine, Rabenoelina, Fanja, Chaintreuil, Carine, Rusciani, Anthony, Maurice, Pascal, Blaise, Sébastien, Romier-Crouzet, Béatrice, El Btaouri, Hassan, Martiny, Laurent, Debelle, Laurent, Duca, Laurent
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2015
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473072/
https://ncbi.nlm.nih.gov/pubmed/26086247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129994
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