Elastin Peptides Signaling Relies on Neuraminidase-1-Dependent Lactosylceramide Generation

The sialidase activity of neuraminidase-1 (Neu-1) is responsible for ERK 1/2 pathway activation following binding of elastin peptide on the elastin receptor complex. In this work, we demonstrate that the receptor and lipid rafts colocalize at the plasma membrane. We also show that the disruption of...

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Detaylı Bibliyografya
Asıl Yazarlar: Rusciani, Anthony, Duca, Laurent, Sartelet, Hervé, Chatron-Colliet, Aurore, Bobichon, Hélène, Ploton, Dominique, Le Naour, Richard, Blaise, Sébastien, Martiny, Laurent, Debelle, Laurent
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982818/
https://ncbi.nlm.nih.gov/pubmed/21103358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014010
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