Elastin Peptides Signaling Relies on Neuraminidase-1-Dependent Lactosylceramide Generation

The sialidase activity of neuraminidase-1 (Neu-1) is responsible for ERK 1/2 pathway activation following binding of elastin peptide on the elastin receptor complex. In this work, we demonstrate that the receptor and lipid rafts colocalize at the plasma membrane. We also show that the disruption of...

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Detalhes bibliográficos
Principais autores: Rusciani, Anthony, Duca, Laurent, Sartelet, Hervé, Chatron-Colliet, Aurore, Bobichon, Hélène, Ploton, Dominique, Le Naour, Richard, Blaise, Sébastien, Martiny, Laurent, Debelle, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982818/
https://ncbi.nlm.nih.gov/pubmed/21103358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014010
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