Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis

BACKGROUND: There is microscopic spatial and temporal heterogeneity of pathologic changes in idiopathic pulmonary fibrosis (IPF) lung tissue, which may relate to heterogeneity in pathophysiological mediators of disease and clinical progression. We assessed relationships between gene expression patte...

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Published in:Thorax
Main Authors: DePianto, Daryle J., Chandriani, Sanjay, Abbas, Alexander R., Jia, Guiquan, N’Diaye, Elsa N., Caplazi, Patrick, Kauder, Steven E., Biswas, Sabyasachi, Karnik, Satyajit K., Ha, Connie, Modrusan, Zora, Matthay, Michael A., Kukreja, Jasleen, Collard, Harold R., Egen, Jackson G., Wolters, Paul J., Arron, Joseph R.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472447/
https://ncbi.nlm.nih.gov/pubmed/25217476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2013-204596
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