Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis

BACKGROUND: There is microscopic spatial and temporal heterogeneity of pathologic changes in idiopathic pulmonary fibrosis (IPF) lung tissue, which may relate to heterogeneity in pathophysiological mediators of disease and clinical progression. We assessed relationships between gene expression patte...

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Udgivet i:Thorax
Main Authors: DePianto, Daryle J., Chandriani, Sanjay, Abbas, Alexander R., Jia, Guiquan, N’Diaye, Elsa N., Caplazi, Patrick, Kauder, Steven E., Biswas, Sabyasachi, Karnik, Satyajit K., Ha, Connie, Modrusan, Zora, Matthay, Michael A., Kukreja, Jasleen, Collard, Harold R., Egen, Jackson G., Wolters, Paul J., Arron, Joseph R.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472447/
https://ncbi.nlm.nih.gov/pubmed/25217476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2013-204596
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