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Molecular mapping of interstitial lung disease reveals a phenotypically distinct senescent basal epithelial cell population

Compromised regenerative capacity of lung epithelial cells can lead to cellular senescence, which may precipitate fibrosis. While increased markers of senescence have been reported in idiopathic pulmonary fibrosis (IPF), the origin and identity of these senescent cells remain unclear, and tools to c...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: DePianto, Daryle J., Heiden, Jason A. Vander, Morshead, Katrina B., Sun, Kai-Hui, Modrusan, Zora, Teng, Grace, Wolters, Paul J., Arron, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119199/
https://ncbi.nlm.nih.gov/pubmed/33705361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.143626
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