Covalent Modification of Bacteriophage T4 DNA Inhibits CRISPR-Cas9

The genomic DNAs of tailed bacteriophages are commonly modified by the attachment of chemical groups. Some forms of DNA modification are known to protect phage DNA from cleavage by restriction enzymes, but others are of unknown function. Recently, the CRISPR-Cas nuclease complexes were shown to medi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:mBio
Main Authors: Bryson, Alexandra L., Hwang, Young, Sherrill-Mix, Scott, Wu, Gary D., Lewis, James D., Black, Lindsay, Clark, Tyson A., Bushman, Frederic D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471564/
https://ncbi.nlm.nih.gov/pubmed/26081634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00648-15
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados