Covalent Modifications of the Bacteriophage Genome Confer a Degree of Resistance to Bacterial CRISPR Systems

The interplay between defense and counterdefense systems of bacteria and bacteriophages has been driving the evolution of both organisms, leading to their great genetic diversity. Restriction-modification systems are well-studied defense mechanisms of bacteria, while phages have evolved covalent mod...

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Bibliographic Details
Published in:J Virol
Main Authors: Liu, Yuepeng, Dai, Li, Dong, Junhua, Chen, Cen, Zhu, Jingen, Rao, Venigalla B., Tao, Pan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654273/
https://ncbi.nlm.nih.gov/pubmed/32938767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01630-20
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