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Impaired natriuretic response to high-NaCl diet plus aldosterone infusion in mice overexpressing human CD39, an ectonucleotidase (NTPDase1)
Extracellular nucleotides acting through P2 receptors facilitate natriuresis. To define how purinergic mechanisms are involved in sodium homeostasis, we used transgenic (TG) mice that globally overexpress human CD39 (hCD39, NTPDase1), an ectonucleotidase that hydrolyzes extracellular ATP/ADP to AMP,...
שמור ב:
| הוצא לאור ב: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Physiological Society
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4469885/ https://ncbi.nlm.nih.gov/pubmed/25877509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00125.2014 |
| תגים: |
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