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Defective renal water handling in transgenic mice over-expressing human CD39/NTPDase1

Ectonucleoside triphosphate diphosphohydrolase-1 hydrolyzes extracellular ATP and ADP to AMP. Previously, we showed that CD39 is expressed at several sites within the kidney and thus may impact the availability of type 2 purinergic receptor (P2-R) ligands. Because P2-Rs appear to regulate urinary co...

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Autors principals: Zhang, Yue, Morris, Kaiya L., Sparrow, Shannon K., Dwyer, Karen M., Enjyoji, Keiichi, Robson, Simon C., Kishore, Bellamkonda K.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433867/
https://ncbi.nlm.nih.gov/pubmed/22622462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00060.2012
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